| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5283190 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Dynamic kinetic resolution (DKR) of various fluorinated aryl alcohols by a combination of lipase-catalyzed enzymatic resolution with in situ ruthenium-catalyzed alcohol racemization is described. (R)-Selective Candida antarctica lipase B (CALB) was employed for transesterification of different fluoroaryl alcohols in DKR reactions delivering the corresponding acetates in high yield (⩾97%) with excellent enantiomeric excess (⩾98%).
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Authors
Krisztián Bogár, Jan-E. Bäckvall,