A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain

Article ID	Journal	Published Year	Pages	File Type
5283191	Tetrahedron Letters	2007	5 Pages	PDF

Abstract

A straightforward method for the synthesis of nucleotide analogues bearing a phosphorothioate moiety at the terminal position of the polyphosphate chain is described.

Keywords

ADE GUA GTPγS HYP ADPβS ATPγS 2,2′-dithiodipyridine GDPβS Nucleotide analogues URA chemical synthesis cyt Phosphorothioates

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain

Authors

Joanna Kowalska, Magdalena Lewdorowicz, Edward Darzynkiewicz, Jacek Jemielity,