Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5283368 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
[5-Acyl-2-(trimethylsilyl)phenyl]iodonium triflates were prepared for the generation of benzynes bearing ketone function. Treatment of the iodonium triflates with Bu4NF in CH2Cl2 in the presence of furan at room temperature gave 6-acyl-1,4-epoxy-1,4-dihydronaphthalenes in high yields. The mild conditions and the tolerance of the ketone function on benzyne generation are attributable to the advantage of hypervalent iodine compounds.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tsugio Kitamura, Yoshiki Aoki, Shingo Isshiki, Kanako Wasai, Yuzo Fujiwara,