| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5283370 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Conditions have been developed for the selective reduction of N-Boc-protected amino acid-derived secondary amides, avoiding the formation of overreduction and cyclic urea byproducts. The method is showcased by the efficient formal synthesis of NK-1 antagonist LY303870.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Eric A. Voight, Matthew S. Bodenstein, Norihiro Ikemoto, Michael H. Kress,