| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5283557 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A new method for the synthesis of functionalized biaryl α-ketophosphonic acids has been developed. The key step involves the use of sodium bromobenzoyl phosphonates to react with polymer-bound boronic acids via microwave-assisted aqueous Suzuki coupling. This approach provides rapid access to a wide range of diverse biaryl analogues containing an α-ketophosphonic acid moiety.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xianfeng Li, Anna Katrin Szardenings, Christopher P. Holmes, Liang Wang, Ashok Bhandari, Lihong Shi, Marc Navre, Larry Jang, J. Russell Grove,