Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5283818 | Tetrahedron Letters | 2007 | 6 Pages |
Abstract
The oxidative radical cyclization of α-fluoroacetophenones in the presence of olefins offers an efficient access to 2-fluorotetralones. Fluorinated starting materials can be prepared from α-bromoacetophenones. The reaction was optimized with respect to a future application in the synthesis of 18-fluorine labeled compounds, where reaction times are a critical aspect.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Markus R. Heinrich,