Facile synthesis of primary amides and ketoamides via a palladium-catalysed carbonylation-deprotection reaction sequence

Primary amides and ketoamides have been synthesised in good yields in two steps from alkenyl/aryl iodides. The reaction sequence involves palladium-catalysed carbonylation in the presence of t-BuNH2 followed by selective cleavage of the t-Bu group using TBDMSOTf.