| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5284008 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
A catalytic, green and practical method for Friedel-Crafts hydroxyalkylation of mucohalic acid has been accomplished. Reaction of mucohalic acids with various electron-rich aromatic compounds in the presence of catalytic (1 mol % to 10 mol %) In(OTf)3 or Brönsted acid, such as H2SO4 in acetic acid provides γ-aryl γ-butenolides in moderate to excellent yield.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ji Zhang, Peter G. Blazecka, Timothy T. Curran,