Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5284063 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
Asymmetric dihydroxylation of 1,1-disubstituted and 1,3-disubstituted allenes can be used to synthesize chiral α-hydroxy ketones. We have also obtained α,αâ²-dihydroxy ketones with high enantioselectivity from 1,3-disubstituted allenes. Low conversion of the dihydroxylation of chiral allenes can be used as a kinetic resolution of sterically hindered allenes.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Steven A. Fleming, Renmao Liu, J. Ty Redd,