| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5284084 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
We report the synthesis and characterization of two oligonucleotides (a tetramer and a 19-mer) labelled with a fluorescent oligothiophene and obtained by means of the phosphoramidite of the fluorophore. The conjugate compounds were synthesized in solid phase and characterized by means of mass spectrometry, multinuclear NMR, UV-vis and photoluminescence spectroscopies. The results show that this approach is suitable as a general route for the preparation of oligonucleotides labelled with oligothiophene-based fluorophores.
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Authors
Massimo L. Capobianco, Marina Naldi, Massimo Zambianchi, Giovanna Barbarella,