Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5284120 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
The reaction of 2-(arylamino)-1-(methylthio)-1-tosylethenes (4) with hydrogen iodide in refluxing toluene gave 3-tosyl-2-(tosylmethyl)quinoline derivatives (6) in good yields. In this reaction, hydrogen iodide dose not only reductively removes the methylthio group of 4 to form an intermediary 1-(arylamino)-2-tosylethene (5), but also serves as a protic catalyst for the subsequent dimeric cyclization of 5 to lead to the quinoline derivatives (6).
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shoji Matsumoto, Katsuyuki Ogura,