| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5284142 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
We report an expedient method for the heteroarylation of acetone under tin-free conditions. The coupling is performed using the commercially available enol silane of acetone (2-trimethylsilyloxypropene) and a corresponding aryl bromide, chloride or triflate under microwave-assisted conditions, with tris(dibenzylideneacetone)dipalladium (Pd2(dba)3) or palladium acetate (Pd(OAc)2) and 2-(2â²,6â²-dimethoxybiphenyl)dicyclohexylphosphine (S-Phos) as the catalyst system.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Harry R. Chobanian, Ping Liu, Marc D. Chioda, Yan Guo, Linus S. Lin,