Article ID Journal Published Year Pages File Type
5284157 Tetrahedron Letters 2007 4 Pages PDF
Abstract
Silylation of alcohols with hexamethyldisilazane (HMDS) in dichloromethane provides the corresponding silyl ethers in almost quantitative yields at room temperature using 1-3 mol % of sulfonic acid-functionalized silica. Additionally, the catalyst displays a high activity and thermal stability (up to 240 °C) and it can be easily recovered and reused for at least 20 reaction cycles without loss of reactivity.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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