Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5284423 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
A highly stereoselective reductive amination method was developed based on in situ generated sodium acyloxyborohydride and was successfully applied to a steroidal skeleton with various amine sources. High yield (96%) and a de of up to 95% were achieved by modifying the reducing reagent. The effect of this reagent will be discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sharaf Nawaz Khan, Seon-Yun Bae, Hong-Seok Kim,