Article ID Journal Published Year Pages File Type
5284423 Tetrahedron Letters 2005 4 Pages PDF
Abstract
A highly stereoselective reductive amination method was developed based on in situ generated sodium acyloxyborohydride and was successfully applied to a steroidal skeleton with various amine sources. High yield (96%) and a de of up to 95% were achieved by modifying the reducing reagent. The effect of this reagent will be discussed.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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