Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5284436 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
Semipermanent side-chain protection of Orn and Lys with p-nitrobenzyloxycarbonyl (pNZ) for Fmoc/tBu chemistry does not result in the unwanted removal of α-Fmoc that occurs when groups such as Alloc are used for the same application. Furthermore, pNZ can be used in conjuction with p-nitrobenzyl ester (pNB) to prepare cyclic peptides.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Albert Isidro-Llobet, Mercedes Álvarez, Fernando Albericio,