| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5285391 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
An efficient synthesis of pyrimido[4,5-b][1,4]oxazines is realized using 5-bromouracil. Substitution in the 2-position was performed by palladium-mediated cross-coupling reactions (Suzuki, Stille and carbon-nitrogen bond forming process) and by SNAr reactions. Microwave-heating is also used for high-speed synthesis.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and functionalization of 2-hydroxypyrimido[4,5-b][1,4]oxazine](/preview/png/5285391.png "First Page Preview: Synthesis and functionalization of 2-hydroxypyrimido[4,5-b][1,4]oxazine")
Authors
S. El Kazzouli, G. Lavecchia, S. Berteina-Raboin, G. Guillaumet,