Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5285401 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A key improvement in the α-amido alkylation between generic silicon-based Ï-nucleophiles and cyclic N,O-acetals catalyzed by HNTf2 and TIPSOTf is achieved with the development of solvent-free variant. This has led to a simple and totally eco-friendly procedure now enabling the reaction to proceed at very low catalyst loadings.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marie-José Tranchant, Charlotte Moine, Raja Ben Othman, Till Bousquet, Mohamed Othman, Vincent Dalla,