Article ID Journal Published Year Pages File Type
5285401 Tetrahedron Letters 2006 4 Pages PDF
Abstract
A key improvement in the α-amido alkylation between generic silicon-based π-nucleophiles and cyclic N,O-acetals catalyzed by HNTf2 and TIPSOTf is achieved with the development of solvent-free variant. This has led to a simple and totally eco-friendly procedure now enabling the reaction to proceed at very low catalyst loadings.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , , ,