Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5285434 | Tetrahedron Letters | 2005 | 6 Pages |
Abstract
The first enantiospecific total synthesis of gardnerine and gardnutine has been achieved from 6-methoxy-d-tryptophan via the asymmetric Pictet-Spengler reaction, a stereocontrolled intramolecular enolate driven palladium-mediated cross-coupling reaction and a chemospecific, regiospecific hydroboration/oxidation sequence as key steps.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hao Zhou, Dongmei Han, Xuebin Liao, James M. Cook,