| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5285482 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
A series of new chiral Tf-based sulfamide-amine alcohols (Tf-based SAA) were synthesized from natural chiral (â)-ephedrine and aziridines derived from commercially available chiral amino alcohols. Among these ligands, 3a was found to be more effective for the addition reaction of alkynylzinc to aromatic aldehyes at room temperature without using other kinds of metal species, providing 81-92% ee and up to 99% yields.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hongwang Li, Yongbo Huang, Wei Jin, Feng Xue, Boshun Wan,