Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5285655 | Tetrahedron Letters | 2008 | 5 Pages |
Abstract
A straightforward and efficient method for the synthesis of 1,2-dihydroisoquinolines via the one-pot, three-component reaction of an isocyanide, isoquinoline and a strong CH-acid in water without using any catalyst at 70 °C is reported. The method offers several advantages including high yields of products and an easy work-up procedure.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ahmad Shaabani, Ebrahim Soleimani, Jafar Moghimi-Rad,