Article ID Journal Published Year Pages File Type
5285655 Tetrahedron Letters 2008 5 Pages PDF
Abstract
A straightforward and efficient method for the synthesis of 1,2-dihydroisoquinolines via the one-pot, three-component reaction of an isocyanide, isoquinoline and a strong CH-acid in water without using any catalyst at 70 °C is reported. The method offers several advantages including high yields of products and an easy work-up procedure.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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