| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5285737 | Tetrahedron Letters | 2006 | 6 Pages |
Abstract
The structure-diastereoselectivity relationships in the IMDA reactions of the terminally activated (E,E,E)-nona-1,6,8-trienes have been studied. It is found that the configuration of the C3 position bearing the protected hydroxyl group is crucial to the diastereoselectivity, and the magnitude of the ratio depends on the relative configuration of the C3-C5 positions. The results obtained in this study including the new successful IMDA reactions would be useful for the stereoselective synthesis of natural products containing a bicyclo[4.3.0]non-2-ene carbon skeleton.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Takahiro Suzuki, Natsumi Tanaka, Takehiko Matsumura, Yosuke Hosoya, Masahisa Nakada,