Article ID Journal Published Year Pages File Type
5285880 Tetrahedron Letters 2008 4 Pages PDF
Abstract
Novel distamycin-porphyrin conjugates were synthesized and their interaction with calf thymus DNA was studied. Minor groove binding of the distamycin part of the molecule was confirmed. The porphyrin part of the conjugates exhibited intercalation and the non-specific electrostatic interaction with the phosphate groups of DNA.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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