| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5285957 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A practical synthesis of 4â²-thioribonucleosides starting from inexpensive l-arabinose is described. 1,4-Anhydro-2,3-O-isopropylidene-4-thioribitol, which was prepared by using a novel reductive ring-contraction reaction, was converted to the 5-O-silylated sulfoxides. The Pummerer-type thioglycosylation of the sulfoxides gave the 4â²-thioribonucleosides stereoselectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yuichi Yoshimura, Tetsuya Kuze, Mari Ueno, Fumiko Komiya, Kazuhiro Haraguchi, Hiromichi Tanaka, Fumitaka Kano, Kohei Yamada, Kazuhiro Asami, Nobuaki Kaneko, Hiroki Takahata,