| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5286475 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A general strategy for the preparation of enediyne-bridged amino acids has been disclosed. A cross-coupling reaction between amino- and carboxyl-modified amino acids under Sonogashira reaction conditions gave a protected enediyne-peptide conjugate. The model obtained can be used as a template in studies of Bergman cycloaromatization or peptide conformational preferences induced by the presence of the enediyne moiety.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ivanka JeriÄ, Hueih-Min Chen,