| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5286631 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
A fast and efficient method has been developed for the bromination of isoxazoles and pyrazoles using microwave irradiation. In this method, N-bromosuccinimide was used in different acid solvents according to the reactivity of the substrates to give mono-brominated isoxazoles and pyrazoles in good yields. Trifluoroacetic acid was found to be the best solvent for highly unreactive isoxazoles and pyrazoles.
Graphical abstractA fast and efficient bromination method has been developed for isoxazoles and pyrazoles using microwave irradiation. This method gives good yields for the bromination of highly unreactive isoxazoles and pyrazoles.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
