| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5286739 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
Ene cyclisation of a variety of 4-aza-1,7-dienes affords 3,4-disubstituted piperidines. In particular, cyclisation of diesters 14 and 20 catalysed by MeAlCl2 gives the corresponding trans 3,4-disubstituted piperidines with diastereomeric ratios of >200:1.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stephen M. Walker, Jodi T. Williams, Alexander G. Russell, John S. Snaith,