Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5286987 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
TeocCl (Teoc: C(O)O(CH2)2TMS) generated in situ was conveniently used for trans-protection of the N-Bn piperidine intermediate to N-Teoc piperidine. Later, deprotection of the Teoc group and the subsequent quinuclidine ring formation was achieved with CsF in a domino fashion to afford the quinine alkaloids.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Junji Igarashi, Yuichi Kobayashi,