Article ID Journal Published Year Pages File Type
5286987 Tetrahedron Letters 2005 4 Pages PDF
Abstract
TeocCl (Teoc: C(O)O(CH2)2TMS) generated in situ was conveniently used for trans-protection of the N-Bn piperidine intermediate to N-Teoc piperidine. Later, deprotection of the Teoc group and the subsequent quinuclidine ring formation was achieved with CsF in a domino fashion to afford the quinine alkaloids.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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