| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5287018 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Zirconocene catalyzed cyclization of 2-(5-methoxy-3-penten-1-yl)styrene in the presence of organomagnesium reagents was studied. The cyclization proceeded in high isolated yields (up to 84%) with excellent trans-selectivity (>98%), which is unusual for the formation of cyclohexane derivatives. Catalytic cyclization in the presence of Cp2ZrCl2 proceeded as well with similar results. The reaction with (R,R)-(EBTHI)2ZrCl2 gave a cis/trans mixture of 5 in low yield and poor ee.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pavel Herrmann, Martin Kotora,