Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5287032 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Ditosylation of two adjacent 6-positions of γ-cyclodextrin, subsequent mono-substitution with l-cysteine and final condensation with dansyl chloride afford the title compounds whose clockwise and counterclockwise isomers are separated from each other and their regio-chemistry is unambiguously determined by a new strategy based on the combination of enzyme degradation of the hetero-bifunctional γ-cyclodextrin to the corresponding disubstituted maltotriose and fragmentation analysis of the latter by PSD-MS technique.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Hua Yu, Yuji Makino, Makoto Fukudome, Ru-Gang Xie, De-Qi Yuan, Kahee Fujita,