| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5287253 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
A simple, efficient, and general two-step synthesis to bromo-pyridine carbaldehyde scaffolds is described. This direct route involves sequential reactions employing the dibromination of bromo-picolines followed by hydrolysis using an aqueous solution of calcium carbonate. Bromo-pyridine carbaldehyde scaffolds 1-7 were obtained in good overall yield. Bromo-dibromomethyl-pyridine intermediates have been isolated and characterized.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ashis Baran Mandal, John Kallikat Augustine, Anna Quattropani, Agnes Bombrun,