| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5287410 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
An anionic chiral auxiliary-mediated asymmetric alkylation of carbamate 2 affords 3,3-disubstituted isoindolinones 3 in moderate to high de. The chiral auxiliary can be removed and recovered under mild conditions, and the resulting enantiopure lactams further elaborated.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Daniel L. Comins, Anne-Cécile Hiebel,