| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5288171 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
Lipase-catalyzed enantioselective amidation was performed by reacting the racemic amine with aliphatic acids in nonsolvent system. The reaction equilibrium was shifted towards amide synthesis by the removal of water under reduced pressure. This methodology avoids the use of activating agents and hazardous solvents.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ashok K. Prasad, Mofazzal Husain, Brajendra K. Singh, Rajinder K. Gupta, Vijay K. Manchanda, Carl E. Olsen, Virinder S. Parmar,