| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5288469 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
A series of novel conformationally rigid pyrrolidinyl peptide nucleic acids (PNA) based on d-prolyl-2-aminocyclopentanecarboxylic acid (ACPC) backbones was synthesized and the DNA binding properties of these PNAs studied. The PNA containing (1S,2S)-ACPC can form a very stable 1:1 complex with complementary DNA in a sequence-specific manner.
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Authors
Chaturong Suparpprom, Choladda Srisuwannaket, Polkit Sangvanich, Tirayut Vilaivan,