| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5288491 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
The reaction of alkynylzinc bromides with benzyl bromides or chlorides in the presence of a catalytic amount of Pd(DPEphos)Cl2 in THF at 23 °C cleanly produces the corresponding benzylated alkynes in 73-97% yields. With 10â3 mol % of Pd(DPEphos)Cl2, the maximum turnover number of 7.1 Ã 104 has been observed for the formation of PhCCCH2Ph.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mingxing Qian, Ei-ichi Negishi,