| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5288550 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A robust method has been developed to couple a wide variety of pyridin-2-ones and aryl halides. This C-N bond forming reaction makes use of catalytic copper(I) iodide and the ligand 8-hydroxyquinoline. These conditions tolerate a wide degree of functionality on both the aryl halide and pyridin-2-one reactants and have resulted in numerous examples being synthesized.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kevin J. Filipski, Jeffrey T. Kohrt, Agustin Casimiro-Garcia, Chad A. Van Huis, Danette A. Dudley, Wayne L. Cody, Christopher F. Bigge, Shrilakshmi Desiraju, Shaoyi Sun, Samarendra N. Maiti, Mohamad R. Jaber, Jeremy J. Edmunds,