| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5288899 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A three-component Mannich reaction of 3a-hydroxyfuroindoline (3), β-ketoester and formaldehyde was employed as an efficient and concise method to synthesize naturally-occurring (+)-Madindolines A (1) and B (2). The scope and limitations of the Mannich reaction with 3 are described.
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Authors
Tomoyasu Hirose, Toshiaki Sunazuka, Daisuke Yamamoto, Eisuke Kaji, Satoshi Åmura,