Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5289073 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
A short and efficient synthesis of (R)-(+)-goniothalamin 1 and (R)-(+)-goniothalamin oxide 2 is described. During this approach, the sulfoxide-modified Julia olefination was used as a key step to connect aldehyde 5 to sulfoxide 6. The desired styryl-containing adduct is obtained in good yield and with excellent E/Z selectivity.
Related Topics
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Chemistry
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Authors
JiÅÃ PospÃÅ¡il, István E. Markó,