Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5290085 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Aromatic bromination on various aromatic systems with different substitutions was performed in the presence of alkyl bromide and sodium hydride in DMSO. Mono-bromination on a wide range of substrates was achieved by selecting proper alkyl bromides and controlling its amount. Further bromination could happen with more active alkyl bromides and additional amount of bromides and sodium hydride. The yields ranged from moderate to excellent. In addition, reaction mechanism was postulated to explain our observations.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
MaoJun Guo, Laszlo Varady, Demosthenes Fokas, Carmen Baldino, Libing Yu,