| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5290286 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Cyclization of various bisacylated hydrazines and pyrazolidines using DBU or sodium hydride leads to the formation of various mono-, bi- and tricyclic pyrazolone scaffolds in 41-98% yield. The convergent nature by which the precyclization intermediates are constructed allows for rapid derivatization about the pyrazolone core.
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Authors
Todd A. Brugel, Tomas Hudlicky, Michael P. Clark, Adam Golebiowski, Mark Sabat, Mary Ann A. Endoma, Vu Bui, David Adams, Matthew J. Laufersweiler, Jennifer A. Maier, Roger G. Bookland, Biswanath De,