Article ID Journal Published Year Pages File Type
5290309 Tetrahedron Letters 2006 4 Pages PDF
Abstract
N-Alkylimines derived from cyclobutanones have not been evaluated in depth as building blocks for organic synthesis, although these compounds are, among others, good precursors for interesting 3-arylcyclobutylamines. The reduction of various N-alkyl-N-(3-arylcyclobutylidene)amines with LiAlH4 yielded cis-substituted cyclobutylamines as the only stereoisomers. When borane was used as a reducing agent, an intermediate imine-borane complex could be isolated as a stable compound.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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