Article ID Journal Published Year Pages File Type
5291969 Tetrahedron Letters 2006 6 Pages PDF
Abstract
A new, convenient, efficient and cost-effective one-pot solid supported synthesis of 2,4,6-triarylpyridines from benzylideneacetophenones and urea, thiourea or their derivatives, using Bi(III) nitrate-Al2O3 is described. The reaction seems to proceed via β-oxygenation of Bi(III)-enolized benzylideneacetophenone followed by Michael addition, heteroannulation with simultaneous retro aldol disproportionation and subsequent catalytic oxidation and dehydration.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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