Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5292103 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
We report on the optimisation of the synthesis of 5-aminoindolizines with respect to microwave heating, solvent, substrate/amine stoichiometry and base addition. A new improved protocol was developed and tested for its applicability to primary and secondary amines of varying nucleophilicity and steric demand.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
P. Tielmann, C. Hoenke,