Article ID Journal Published Year Pages File Type
5292121 Tetrahedron Letters 2006 4 Pages PDF
Abstract
A simple Ni-catalysed cross-coupling protocol for amino-heteroaryl chlorides with alkylzinc reagents has been developed. The alkylzinc reagents can be commercially available dialkylzincs or alkylzinc halides, or can be conveniently generated in situ from diethylzinc and primary alkyl bromides in the presence of the same inexpensive Ni catalyst used to effect the subsequent coupling reaction.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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