Article ID Journal Published Year Pages File Type
5292122 Tetrahedron Letters 2006 4 Pages PDF
Abstract
The total synthesis of antimalarial and cyclooxygenase inhibitors, racemosol and de-O-methylracemosol, is described. The key steps involved the lateral lithiation reaction of ortho-methyl tolulate and the pyran formation via a tandem demethylation-cyclization reaction.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Total synthesis of racemosol and de-O-methylracemosol, potent cyclooxygenase (COX) inhibitors and antimalarial agents
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