| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5309776 | Tetrahedron Letters | 2016 | 4 Pages |
Abstract
L-755,805, 1, a hexacyclic polyketide with a novel ring system, has been isolated from an actinomycete culture, MA7150. The planar structure was determined from interpretation of spectroscopic data. 1 inhibits 125I-endothelin binding to ET-A and ET-B receptors with IC50's of 11 and 3.9 μM.
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Authors
Y.K.Tony Lam, Otto Hensens, Gregory Helms, David Jr., Mary Nallin, Jack Smith, Suzanne Gartner, Lucia Herranz Rodriguez, Siobhan Stevens-Miles,