Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5349758 | Applied Surface Science | 2014 | 8 Pages |
Abstract
In this study, polypyrrole-graft-chitosan (PPy-g-CS) copolymer was chemically synthesized and its structural and morphological properties characterized by FTIR, UV-vis, SEM, XRD, TGA and zeta-potential techniques. The results revealed that there were strong interactions between PPy and CS chains. The electrical conductivity of CS increased to semiconducting range by grafting. The crystallinity and thermal stability of PPy-g-CS copolymer improved when compared to CS. The copolymer was tested against various bacterial and fungal strains at various concentrations and results obtained were compared with the reference antibiotics. The results indicated that the antibacterial activity of PPy-g-CS copolymer was stronger than CS and PPy alone. The antibacterial activity of the PPy-g-CS copolymer observed to increase with rising concentration, and showed stronger activity against bacteria than Penicillin (10Â mg), Rifampicin (5Â mg) and Trimethoprim (25Â mg), whereas showed equipotent activity with Amikacin (30Â mg) and Erythromycin (15Â mg) antibiotics.
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Authors
Mehmet Cabuk, Yusuf Alan, Mustafa Yavuz, Halil Ibrahim Unal,