| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5352859 | Applied Surface Science | 2013 | 6 Pages |
Abstract
⺠Iron oxide nanoparticles with high magnetization and superparamagnetic properties were produced by laser pyrolysis. ⺠NPs internalization in the cytoplasm has a concentration dependent anti proliferative effect on MCF-7 tumor cells. ⺠The loading mechanism of Violamycine B1 on NP is assumed to rely on the electrostatic interactions. ⺠The anti-tumor activity of VB1 loaded on NP was maintained but the apoptosis process is delayed. ⺠NP drug delivery system should provide more drug accumulation at tumor site reducing the side effects of chemotherapy.
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Authors
A. Marcu, S. Pop, F. Dumitrache, M. Mocanu, C.M. Niculite, M. Gherghiceanu, C.P. Lungu, C. Fleaca, R. Ianchis, A. Barbut, C. Grigoriu, I. Morjan,