Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5356157 | Applied Surface Science | 2012 | 7 Pages |
Abstract
⺠We obtained implants from indomethacin cores coated with PLGA:PEG films grown by MAPLE. ⺠The implants were studied in vitro, in media close to those encountered inside the body. ⺠The influence of the molecular weight of PEG (1450 Da versus 10 kDa) was investigated. ⺠PEG of high molecular weight enhanced the blood compatibility of the implants. ⺠PEG of high molecular weight increased the drug release rates from the implants.
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Physical and Theoretical Chemistry
Authors
Irina Alexandra Paun, Antoniu Moldovan, Catalin Romeo Luculescu, Angela Staicu, Maria Dinescu,