Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5357016 | Applied Surface Science | 2015 | 35 Pages |
Abstract
A Fe-Mn-Si alloy was obtained as alloplastic graft materials for bone implants that need long recovery time period. The surface morphology of the resulted specimens was investigated using scanning electrons microscopy (VegaTescan LMH II, SE detector, 30Â kV), X-ray diffractions (X'Pert equipment) or X-ray dispersive energy analyze (Bruker EDS equipment). This study objective was to evaluate in vivo the mechanisms of degradation and the effects of its implantation over the main metabolic organs. Biochemical, histological, plain X radiography and computed tomography investigations showed good compatibility of the subcutaneous implants in the rat organism. The implantation of the Fe-Mn-Si alloy, in critical size bone (tibiae) defect rat model, did not induced adverse biological reactions and provided temporary mechanical support to the affected bone area. The biodegradation products were hydroxides layers which adhered to the substrate surface. Fe-Mn-Si alloy assured the mechanical integrity in rat tibiae defects during bone regeneration.
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Authors
Mircea Fântânariu, Lucia Carmen TrincÄ, Carmen Solcan, Alina Trofin, Åtefan Strungaru, Eusebiu Viorel Åindilar, Gabriel PlÄvan, Sergiu Stanciu,