| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5358078 | Applied Surface Science | 2011 | 9 Pages |
Abstract
⺠Nanostructured manganese (Mn)-containing thin Ti oxide film (Mn2O3) on pure titanium was produced by hydrothermal treatment. ⺠Mn-incorporated Ti oxide layer released Mn ions from the surface into the solution. ⺠Mn2O3 coating decreased cellular attachment, spreading, proliferation, alkaline phosphatase activity, and osteoblast phenotype gene expression compared with bare titanium surface. ⺠This is the first demonstration that Mn ion in Ti oxide layer does not exert any beneficial effects on osteoblastic cell response, it rather impaired cell function.
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Authors
Jin-Woo Park, Youn-Jeong Kim, Je-Hee Jang,